Solutions porfolio
SymbiO-Derm
Our solution for Oxygen delivery in severe wounds treatment, based on a Dermal Regeneration Photosynthetic Matrix (DRPM). The device allows for the treatment of full-thickness skin wounds. This device can be customized for in-situproduction of pro-regeneration molecules.
Specifically designed for the SymbiO-Derm treated patients, the illumination device allows the direct stimulation of the DRPM with blue-LED technology, to achieve in-situ Oxygen delivery. Its thin and flexible design allows to comfortably wrap the treated area, for an optimized blue light delivery.
Photosynthetic hydrogel
Hydrogel designed for partial-thickness wounds, with mechanical properties that allows its use in different wound locations and ambulatory use. Will have the same Oxygen-production and customizable properties of SymbiO-Derm. Currently in development.
Decellularized scaffold
Development of our own collagen scaffold for the production of SymbiO-Derm. This will allow us to reduce the cost of the DRPM and have a 100% independent fabrication. Currently in Development.
Transplant organs preservation
Technology based on perfussion of procured organ that improves the lifespan and quality of organs before transplantation. The internal oxygenation of the procured organ significantly extends its viability, allowing a higher chance of transplant success.
Validation to Date
Phase I Clinical Data
Publications
Photosymbiosis for Biomedical Applications
Development of photosynthetic biomaterials for in vitro tissue engineering
Generation of Viable Plant-Vertebrate Chimeras
Use of photosynthetic transgenic cyanobacteria to promote lymphangiogenesis in scaffolds for dermal regeneration
Acta biomaterialia
Photosynthetic biomaterials: A pathway towards autotrophic tissue engineering
Development of photosynthetic sutures for the local delivery of oxygen and recombinant growth factors in wounds
Development of a Novel Perfusable Solution for ex vivo Preservation: Towards Photosynthetic Oxygenation for Organ Transplantation
Towards autotrophic tissue engineering: Photosynthetic gene therapy for regeneration
Towards a biotechnological platform for the production of human pro-angiogenic growth factors in the green alga Chlamydomonas reinhardtii
A First in Human Trial Implanting Microalgae Shows Safety of Photosynthetic Therapy for the Effective Treatment of Full Thickness Skin Wounds
Research and Production Facility
SymbiOx Ltda has more than 30 m2 of fully equipped laboratories for the in-vitro analysis, microalgae cultivation and production of the photosynthetic wound dressings.
Our facility includes a microscopy unit, autoclaving and material sterilization system, laminar flow hood, cryopreservation unit, bioreactors for the growth and cultivation of microalgae and CO2 incubators for animal cells.
We are strategically located in the innovation ecosystem of the Pontificia Universidad Católica de Chile, which facilitates interdisciplinary work with different actors of the R & D process.